PhD Position in Medicine (University of Oulu)

About the job Colorectal cancer, the third most common cancer, is a highly heterogeneous disease at both molecular and morphological levels. Its progression is shaped by complex interactions between tumor cells and the surrounding stromal and immune cells. Our research group focuses on three key areas: (1) identifying the factors that drive colorectal cancer heterogeneity, (2) uncovering the role of tumor-host interactions in disease progression, and (3) developing novel biomarkers to advance precision medicine. As a doctoral researcher in our group, you will participate in the analysis of large colorectal cancer cohorts. You will apply techniques such as multiplex immunohistochemistry, in situ hybridization, spatial transcriptomics to uncover the molecular variations that drive tumor phenotypes in colorectal cancer. You will apply data analysis methods and bioinformatics analyses to analyze large-scale molecular data. The findings of the project could refine future tumor classification systems, aid in developing novel biomarkers, and enable more personalized treatment approaches. The doctoral training will give you a strong background for future tissue-based research related to cancer biology, tumor immunology, and bioinformatics. It will offer rich opportunities for networking, mobility, and further career development after completing the PhD in three years. What we offer? The support of an experienced and enthusiastic research team. A dynamic research environment which promotes personal and professional growth as a scientist. Possibility to gain expertise in cutting-edge tissue analysis methods such as multiplex immunohistochemistry and in situ hybridization, as well as sequencing-based molecular pathological methods. Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits. Development and career options of the big organization. Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us. Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu. We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers. Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu. Who are you? In order to succeed and enjoy the position, we expect from you: Master’s or equivalent degree (e.g. licentiate) in biochemistry, biomedicine, bioinformatics, cell biology, data analysis, genetics, medicine, molecular biology, molecular genetics, or related fields Strong motivation to learn and apply new research methods relevant to the project Excellent communication and teamwork skills Fluent in written and spoken English We also appreciate Previous experience in bioinformatics analyses and/or tissue/molecular analysis methods is considered an advantage Background knowledge in cancer biology Please see also the requirements of the University of Oulu Graduate School (UniOGS) Salary Doctoral researchers selected in the pilot programme will by default be offered a three-year (36 month) fixed-term full-time employment contract by University of Oulu. These positions are available for highly motivated and talented researchers wishing to undertake and complete training for a research-focused doctoral degree, starting January 1, 2025 at the earliest. The selected applicants are expected to start their project no later than February 1, 2025. A six-month trial period is applied in the position. The salary will be based on the levels 2-4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2500-2800 € per month (before taxes). How to apply? Interested? If yes, please apply by 23.10.2024 (23:59 Finnish local time) through our recruitment system. The application should be written in English and include the following: A motivation letter (max. 2 pages) summarizing your professional experience and expertise and describing why you are a good fit for this position. Also, information on personal research interests, experience and career plans are valuable to provide here. Curriculum Vitae (max. 2 pages). A recommended CV template can be found on the Finnish Advisory Board on Research Integrity website. Certificates/Diplomas Scanned copy of the original relevant master’s degree certificates and transcript of records and, when necessary, official translations to Finnish or English. Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Applications received after the call deadline will not be considered. We welcome applicants from all backgrounds, such as people of different ages, genders and lingual, cultural or minority groups. Contact Information If you have any further questions, please contact Juha Väyrynen (juha.vayrynen(at)oulu.fi). If you apply for this position please say you saw it on Academicoxy

About the job

Colorectal cancer, the third most common cancer, is a highly heterogeneous disease at both molecular and morphological levels. Its progression is shaped by complex interactions between tumor cells and the surrounding stromal and immune cells. Our research group focuses on three key areas: (1) identifying the factors that drive colorectal cancer heterogeneity, (2) uncovering the role of tumor-host interactions in disease progression, and (3) developing novel biomarkers to advance precision medicine.

As a doctoral researcher in our group, you will participate in the analysis of large colorectal cancer cohorts. You will apply techniques such as multiplex immunohistochemistry, in situ hybridization, spatial transcriptomics to uncover the molecular variations that drive tumor phenotypes in colorectal cancer. You will apply data analysis methods and bioinformatics analyses to analyze large-scale molecular data. The findings of the project could refine future tumor classification systems, aid in developing novel biomarkers, and enable more personalized treatment approaches.

The doctoral training will give you a strong background for future tissue-based research related to cancer biology, tumor immunology, and bioinformatics. It will offer rich opportunities for networking, mobility, and further career development after completing the PhD in three years.

What we offer?

The support of an experienced and enthusiastic research team.
A dynamic research environment which promotes personal and professional growth as a scientist.
Possibility to gain expertise in cutting-edge tissue analysis methods such as multiplex immunohistochemistry and in situ hybridization, as well as sequencing-based molecular pathological methods.
Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits.
Development and career options of the big organization.
Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.

Who are you?

In order to succeed and enjoy the position, we expect from you:

Master’s or equivalent degree (e.g. licentiate) in biochemistry, biomedicine, bioinformatics, cell biology, data analysis, genetics, medicine, molecular biology, molecular genetics, or related fields
Strong motivation to learn and apply new research methods relevant to the project
Excellent communication and teamwork skills
Fluent in written and spoken English

We also appreciate

Previous experience in bioinformatics analyses and/or tissue/molecular analysis methods is considered an advantage
Background knowledge in cancer biology
Please see also the requirements of the University of Oulu Graduate School (UniOGS)

Salary

Doctoral researchers selected in the pilot programme will by default be offered a three-year (36 month) fixed-term full-time employment contract by University of Oulu. These positions are available for highly motivated and talented researchers wishing to undertake and complete training for a research-focused doctoral degree, starting January 1, 2025 at the earliest. The selected applicants are expected to start their project no later than February 1, 2025. A six-month trial period is applied in the position.

The salary will be based on the levels 2-4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2500-2800 € per month (before taxes).

How to apply?

Interested? If yes, please apply by 23.10.2024 (23:59 Finnish local time) through our recruitment system.

The application should be written in English and include the following:

A motivation letter (max. 2 pages) summarizing your professional experience and expertise and describing why you are a good fit for this position. Also, information on personal research interests, experience and career plans are valuable to provide here.
Curriculum Vitae (max. 2 pages). A recommended CV template can be found on the Finnish Advisory Board on Research Integrity website.
Certificates/Diplomas Scanned copy of the original relevant master’s degree certificates and transcript of records and, when necessary, official translations to Finnish or English.

Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Applications received after the call deadline will not be considered.

We welcome applicants from all backgrounds, such as people of different ages, genders and lingual, cultural or minority groups.